BMPR2 Human shRNA Plasmid Kit (Locus ID 659)
Specifications
| Product Data | |
| Locus ID | 659 |
|---|---|
| Synonyms | BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BMPR2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 659). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001204, NM_033346, NM_001204.1, NM_001204.2, NM_001204.3, NM_001204.4, NM_001204.5, NM_001204.6, BC052985, BC052985.2, BC018743, BC032011, BC035097, BC041039, BC043650, NM_001204.7 |
| UniProt ID | Q13873 |
| Summary | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. provided by RefSeq, May 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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