SSH3BP1 (ABI1) Human shRNA Plasmid Kit (Locus ID 10006)
SKU
TF315014
ABI1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 10006 |
|---|---|
| Synonyms | ABI-1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | ABI1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 10006). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001012750, NM_001012751, NM_001012752, NM_001178116, NM_001178119, NM_001178120, NM_001178121, NM_001178122, NM_001178123, NM_001178124, NM_001178125, NM_005470, NM_001348029, NM_001348030, NM_001348031, NM_001348032, NM_001348033, NM_001348034, NR_145410, NM_001012752.1, NM_001012752.2, NM_001012751.1, NM_001012751.2, NM_005470.1, NM_005470.2, NM_005470.3, NM_001012750.1, NM_001012750.2, NM_001178125.1, NM_001178124.1, NM_001178123.1, NM_001178122.1, NM_001178121.1, NM_001178120.1, NM_001178119.1, NM_001178116.1, BC024254, BC013238, NM_001012750.3 |
| UniProt ID | Q8IZP0 |
| Summary | This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. provided by RefSeq, Sep 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.