Caveolin 1 (CAV1) Human shRNA Plasmid Kit (Locus ID 857)
SKU
TF314183
CAV1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 857 |
|---|---|
| Synonyms | BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CAV1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 857). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001172895, NM_001172896, NM_001172897, NM_001753, NM_001753.1, NM_001753.2, NM_001753.3, NM_001753.4, NM_001172895.1, NM_001172896.1, NM_001172897.1, BC082246, BC082246.1, BC006432, BC009685, NM_001753.5, NM_001172897.2 |
| UniProt ID | Q03135 |
| Summary | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.provided by RefSeq, Mar 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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