KIAA0100 Human shRNA Plasmid Kit (Locus ID 9703)
SKU
TF311980
KIAA0100 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 9703 |
|---|---|
| Synonyms | BCOX; BCOX1; CT101; FMP27 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | KIAA0100 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 9703). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001321560, NM_001321561, NM_014680, NM_014680.1, NM_014680.2, NM_014680.3, BC008591, BC048096, BC050440, BC103726, BC120873, BM999622, NM_001363827, NM_001363828, NM_001363829, NM_001363826, NM_014680.5 |
| UniProt ID | Q14667 |
| Summary | This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. provided by RefSeq, Apr 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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