NQO1 Human shRNA Plasmid Kit (Locus ID 1728)
SKU
TF311109
NQO1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 1728 |
|---|---|
| Synonyms | DHQU; DIA4; DTD; NMOR1; NMORI; QR1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Format | Retroviral plasmids |
| Components | NQO1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 1728). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC000906, BC036581, NM_000903, NM_001025433, NM_001025434, NM_001286137, NM_000903.1, NM_000903.2, NM_001025434.1, NM_001025433.1, NM_001286137.1, BC007659, BC007659.2, BC107739, BM052991, BM452267, BM787983, BM828301, NM_000903.3, NM_001286137.2, NM_001025433.2, NM_001025434.2 |
| UniProt ID | P15559 |
| Summary | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Shipping | Ambient |
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