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PIK3R5 Human shRNA Plasmid Kit (Locus ID 23533)

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TF310423
PIK3R5 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 23533
Synonyms F730038I15Rik; FOAP-2; p101; P101-PI3K
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components PIK3R5 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 23533). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001142633, NM_001251851, NM_001251852, NM_001251853, NM_001251855, NM_014308, NM_014308.1, NM_014308.2, NM_014308.3, NM_001142633.1, NM_001142633.2, NM_001251851.1, NM_001251852.1, NM_001251853.1, NM_001251855.1, BC028212, NM_001251851.2
UniProt ID Q8WYR1
Summary Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. provided by RefSeq, Oct 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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