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Oct4 (POU5F1) Human shRNA Plasmid Kit (Locus ID 5460)

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TF310267
POU5F1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 5460
Synonyms Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components POU5F1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 5460). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq BC020712, NM_001173531, NM_001285986, NM_001285987, NM_002701, NM_203289, NM_002701.1, NM_002701.2, NM_002701.3, NM_002701.4, NM_002701.5, NM_203289.1, NM_203289.2, NM_203289.3, NM_203289.4, NM_203289.5, NM_001173531.1, NM_001173531.2, NM_001285986.1, NM_001285987.1, BC117435, BC069246, BC117437, NM_002701.6
UniProt ID Q01860
Summary This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. provided by RefSeq, Oct 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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