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Ribonuclease H2, subunit A (RNASEH2A) Human shRNA Plasmid Kit (Locus ID 10535)

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TF309797
RNASEH2A - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
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Other products for "Ribonuclease H2, subunit A or NM_006397"

Specifications
Specifications
Product Data
Locus ID 10535
Synonyms AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Format Retroviral plasmids
Components RNASEH2A - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 10535). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_006397, NM_006397.1, NM_006397.2, BC011748, BM664190, NM_006397.3
UniProt ID O75792
Summary The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.provided by RefSeq, Aug 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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