Keratin 80 (KRT80) Human shRNA Plasmid Kit (Locus ID 144501)

SKU
TF307833
KRT80 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
In Control Promo
  $883.00
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Specifications
Specifications
Product Data
Locus ID 144501
Synonyms KB20
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components KRT80 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 144501). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001081492, NM_182507, NM_182507.1, NM_182507.2, BC065180, BC065180.1, BC033114, BC047308, NM_182507.3
UniProt ID Q6KB66
Summary Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.provided by RefSeq, Oct 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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