MEKK1 (MAP3K1) Human shRNA Plasmid Kit (Locus ID 4214)
Specifications
| Product Data | |
| Locus ID | 4214 |
|---|---|
| Synonyms | MAPKKK1; MEKK; MEKK 1; MEKK1; SRXY6 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MAP3K1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 4214). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_005921, NM_005921.1, NM_005921.2 |
| UniProt ID | Q13233 |
| Summary | The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. provided by RefSeq, Mar 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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