Tuberin (TSC2) Human shRNA Plasmid Kit (Locus ID 7249)
Specifications
| Product Data | |
| Locus ID | 7249 |
|---|---|
| Synonyms | LAM; PPP1R160; TSC4 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | TSC2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 7249). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_000548, NM_001077183, NM_001114382, NM_001318827, NM_001318829, NM_001318831, NM_001318832, NM_021055, NM_021056, NM_000548.1, NM_000548.2, NM_000548.3, NM_000548.4, NM_001077183.1, NM_001077183.2, NM_001114382.1, NM_001114382.2, NM_021055.1, BC025364, BC046929, BC150300, BM966762, NM_001363528, NM_001370405, NM_001370404, NM_000548.5 |
| UniProt ID | P49815 |
| Summary | Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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