XRCC4 Human shRNA Plasmid Kit (Locus ID 7518)
Specifications
| Product Data | |
| Locus ID | 7518 |
|---|---|
| Synonyms | SSMED |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | XRCC4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 7518). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | BC005259, NM_001318012, NM_001318013, NM_003401, NM_022406, NM_022550, NM_022406.1, NM_022406.2, NM_022406.3, NM_003401.1, NM_003401.2, NM_003401.3, NM_003401.4, NM_022550.1, NM_022550.2, NM_022550.3, BC005259.1, BC016314, BC016314.1, BC010655, NM_022406.4, NM_003401.5 |
| UniProt ID | Q13426 |
| Summary | The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. provided by RefSeq, Oct 2019 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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