XRN1 Human shRNA Plasmid Kit (Locus ID 54464)

SKU
TF300419
XRN1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 54464
Synonyms SEP1
Vector pRFP-C-RS
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components XRN1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 54464). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free.
RefSeq NM_001042604, NM_001282857, NM_001282859, NM_019001, NM_019001.1, NM_019001.2, NM_019001.3, NM_019001.4, NM_001042604.1, NM_001282859.1, NM_001282857.1, BC039314, BC048104, BC078146, BC141555, NM_001282857.2, NM_019001.5
UniProt ID Q8IZH2
Summary This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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