XRN1 Human shRNA Plasmid Kit (Locus ID 54464)
Specifications
| Product Data | |
| Locus ID | 54464 |
|---|---|
| Synonyms | SEP1 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | XRN1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 54464). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001042604, NM_001282857, NM_001282859, NM_019001, NM_019001.1, NM_019001.2, NM_019001.3, NM_019001.4, NM_001042604.1, NM_001282859.1, NM_001282857.1, BC039314, BC048104, BC078146, BC141555, NM_001282857.2, NM_019001.5 |
| UniProt ID | Q8IZH2 |
| Summary | This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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