BDNF Human shRNA Lentiviral Particle (Locus ID 627)

CAT#: TL306410V

BDNF - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.


USD 1,731.00

5 Weeks*

Size
    • 500 ul each

Product Images

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Specifications

Product Data
Locus ID 627
Synonyms ANON2; BULN2
Vector pGFP-C-shLenti
Format Lentiviral particles
RefSeq NM_001143805, NM_001143806, NM_001143807, NM_001143808, NM_001143809, NM_001143810, NM_001143811, NM_001143812, NM_001143813, NM_001143814, NM_001143815, NM_001143816, NM_001709, NM_170731, NM_170732, NM_170733, NM_170734, NM_170735, NM_170732.1, NM_170732.2, NM_170732.3, NM_170732.4, NM_170733.1, NM_170733.3, NM_001709.1, NM_001709.2, NM_001709.3, NM_001709.4, NM_170731.1, NM_170731.2, NM_170731.3, NM_170731.4, NM_170734.1, NM_170734.2, NM_170734.3, NM_170735.1, NM_170735.2, NM_170735.3, NM_170735.4, NM_170735.5, NM_001143816.1, NM_001143808.1, NM_001143809.1, NM_001143810.1, NM_001143811.1, NM_001143812.1, NM_001143813.1, NM_001143805.1, NM_001143814.1, NM_001143806.1, NM_001143807.1, NM_001143815.1, BC029795, BC029795.1, NM_001709.5, NM_170731.5
UniProt ID P23560
Summary This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples.

For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.