WNT3 (NM_030753) Human Recombinant Protein

CAT#: TP790160

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Purified recombinant protein of Human wingless-type MMTV integration site family, member 3 (WNT3), with C-terminal DDK tag, secretory expressed in CHO cells, 20ug


 Product Datasheet for 'TP790160'

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USD 700.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Human wingless-type MMTV integration site family, member 3 (WNT3), with C-terminal DDK tag, secretory expressed in CHO cells, 20ug
Species Human
Expression Host CHO
Tag C-DDK
Predicted MW 37.4 kDa
Concentration >50 ug/mL as determined by Bradford protein assay
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS,pH7.4,10% glycerol
Reference Data
RefSeq NP_110380
Locus ID 7473
Refseq Size 1506
Cytogenetics 17q21.31-q21.32
Refseq ORF 1065
Synonyms INT4; TETAMS
Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway

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