WNT3 (NM_030753) Human Recombinant Protein
Purified recombinant protein of Human wingless-type MMTV integration site family, member 3 (WNT3), with C-terminal DDK tag, secretory expressed in CHO cells, 20ug
Product Datasheet for 'TP790160'
Specifications
Product Data | |
Description | Purified recombinant protein of Human wingless-type MMTV integration site family, member 3 (WNT3), with C-terminal DDK tag, secretory expressed in CHO cells, 20ug |
Species | Human |
Expression Host | CHO |
Tag | C-DDK |
Predicted MW | 37.4 kDa |
Concentration | >50 ug/mL as determined by Bradford protein assay |
Purity | > 90% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS,pH7.4,10% glycerol |
Reference Data | |
RefSeq | NP_110380 |
Locus ID | 7473 |
Refseq Size | 1506 |
Cytogenetics | 17q21.31-q21.32 |
Refseq ORF | 1065 |
Synonyms | INT4; TETAMS |
Summary | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other products for "WNT3"
Frequently bought together (1)
WNT3 mouse monoclonal antibody, clone OTI1G7 (formerly 1G7)
USD 360.00
Customer
Reviews
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.