PINK1 (NM_032409) Human Recombinant Protein

SKU TP762427

Purified recombinant protein of Human PTEN induced putative kinase 1 (PINK1), nuclear gene encoding mitochondrial protein, Gly349-Pro472, with N-terminal His-ABP tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region (Gly349-Pro472) of PINK1
• Tag: N-His-ABP (Albumin-Binding Protein)
• Predicted MW: 28.8 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_115785
• Locus ID: 65018
• UniProt ID: Q9BXM7
• Cytogenetics: 1p36.12
• RefSeq Size: 2680
• RefSeq ORF: 1743
• Synonyms: BRPK; PARK6
• Summary: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Parkinson's disease