ABCB7 (NM_004299) Human Recombinant Protein

CAT#: TP762113

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Purified recombinant protein of Human ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7), nuclear gene encoding mitochondrial protein,Val431-End, with N-terminal His tag, expressed in E. coli, 50ug


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USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7), nuclear gene encoding mitochondrial protein,Val431-End, with N-terminal His tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Tag N-His
Predicted MW 35.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Reference Data
RefSeq NP_004290
Locus ID 22
Refseq Size 2528
Cytogenetics Xq13.3
Refseq ORF 2259
Synonyms ABC7; ASAT; Atm1p; EST140535
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters

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