Dopamine D2 Receptor (DRD2) (NM_000795) Human Recombinant Protein

CAT#: TP762112

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Purified recombinant protein of Human dopamine receptor D2 (DRD2), transcript variant 1,Ile214-Gln373, with N-terminal His tag, expressed in E. coli, 50ug


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USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human dopamine receptor D2 (DRD2), transcript variant 1,Ile214-Gln373, with N-terminal His tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Tag N-His
Predicted MW 18.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Reference Data
RefSeq NP_000786
Locus ID 1813
Refseq Size 2713
Cytogenetics 11q23.2
Refseq ORF 1329
Synonyms D2DR; D2R
Summary This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Gap junction, Neuroactive ligand-receptor interaction

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