Coilin (COIL) (NM_004645) Human Recombinant Protein

CAT#: TP762089

Purified recombinant protein of Human coilin (COIL),Met1-Lys220, with N-terminal His tag, expressed in E. coli, 50ug


  View other "COIL" proteins (2)

USD 261.00

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Size
    • 50 ug

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Frequently bought together (1)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Met1-Lys220) of COIL
Tag N-His
Predicted MW 24.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_004636
Locus ID 8161
UniProt ID P38432
Cytogenetics 17q22
Refseq Size 2649
Refseq ORF 1728
Synonyms CLN80; p80-coilin
Summary The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Protein Families Stem cell - Pluripotency

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