MMP7 (NM_002423) Human Recombinant Protein

CAT#: TP762086

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Purified recombinant protein of Human matrix metallopeptidase 7 (matrilysin, uterine) (MMP7),Tyr95-End, with N-terminal His tag, expressed in E. coli, 50ug


Product Datasheet for 'TP762086'


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USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human matrix metallopeptidase 7 (matrilysin, uterine) (MMP7),Tyr95-End, with N-terminal His tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the region(Tyr95-End) of MMP7
Tag N-His
Predicted MW 19.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002414
Locus ID 4316
Refseq Size 1147
Cytogenetics 11q22.2
Refseq ORF 801
Synonyms MMP-7; MPSL1; PUMP-1
Summary This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome, Protease
Protein Pathways Wnt signaling pathway

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