KCNT2 (NM_198503) Human Recombinant Protein

CAT#: TP761995

Purified recombinant protein of Human potassium channel, subfamily T, member 2 (KCNT2),Gly957-Arg1012, with N-terminal His-ABP tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Gly957-Arg1012)of KCNT2
• Tag: N-His-ABP (Albumin-Binding Protein)
• Predicted MW: 21.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_940905
• Locus ID: 343450
• UniProt ID: Q6UVM3, A9LNM6
• Cytogenetics: 1q31.3
• Refseq Size: 5909
• Refseq ORF: 3405
• Synonyms: EIEE57; KCa4.2; SLICK; SLO2.1
• Summary: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497).[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane