LAMA3 (NM_000227) Human Recombinant Protein

CAT#: TP761919

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Purified recombinant protein of Human laminin, alpha 3 (LAMA3), transcript variant 2, Asp346-Leu639, with N-terminal HIS tag, expressed in E. coli, 50ug



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USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human laminin, alpha 3 (LAMA3), transcript variant 2, Asp346-Leu639, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding the region(Asp346-Leu639) of LAMA3
Tag N-His
Predicted MW 32.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150 mM NaCl, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000218
Locus ID 3909
Refseq Size 5601
Cytogenetics 18q11.2
Refseq ORF 5172
Synonyms BM600; E170; LAMNA; LOCS
Summary The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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