AGO1 (NM_012199) Human Recombinant Protein

CAT#: TP761918

Purified recombinant protein of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), Gln226-Cys490, with N-terminal HIS tag, expressed in E. coli, 50ug


  View other "AGO1" proteins (3)

USD 261.00

In Stock*

Size
    • 50 ug

Product Images

Frequently bought together (1)
EIF2C1 mouse monoclonal antibody,clone OTI4G1
    • 100 ul

USD 447.00

Other products for "AGO1"

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Gln226-Cys490) of EIF2C1
Tag N-His
Predicted MW 30.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_036331
Locus ID 26523
UniProt ID Q9UL18, B2RAD8
Cytogenetics 1p34.3
Refseq Size 7478
Refseq ORF 2571
Synonyms EIF2C; EIF2C1; GERP95; hAgo1; Q99
Summary This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome

Documents

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.