LATS2 (NM_014572) Human Recombinant Protein
Purified recombinant protein of Human LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2), Met1-Ala237, with N-terminal HIS tag, expressed in E. coli, 50ug
Product Datasheet for 'TP761911'
Specifications
Product Data | |
Description | Purified recombinant protein of Human LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2), Met1-Ala237, with N-terminal HIS tag, expressed in E. coli, 50ug |
Species | Human |
Expression Host | E. coli |
Tag | N-His |
Predicted MW | 25.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0,150 mM NaCl, 10% glycerol |
Reference Data | |
RefSeq | NP_055387 |
Locus ID | 26524 |
Refseq Size | 4098 |
Cytogenetics | 13q12.11 |
Refseq ORF | 3264 |
Synonyms | KPM |
Summary | This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protein Kinase |
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LY402348 | Transient overexpression lysate of LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2) |
USD 495.00 |
|
LC402348 | LATS2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 155.00 |
|
LC810346 | LATS2-knockout Cell lysate from HeLa cell ine, one vial of parental cell line lysate included as control |
USD 495.00 |
USD 335.00