APLP1 (NM_001024807) Human Recombinant Protein

CAT#: TP761802

Purified recombinant protein of Human amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


  View other "APLP1" proteins (2)

USD 261.00

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Size
    • 50 ug

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Frequently bought together (1)
APLP1 Rabbit polyclonal Antibody
    • 100 ul

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length APLP1
Tag N-GST and C-His
Predicted MW 96.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001019978
Locus ID 333
UniProt ID P51693
Cytogenetics 19q13.12
Refseq Size 2450
Refseq ORF 1950
Synonyms APLP
Summary This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane

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