IKK alpha (CHUK) (NM_001278) Human Recombinant Protein

CAT#: TP761707

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Purified recombinant protein of Human conserved helix-loop-helix ubiquitous kinase (CHUK), full length, with N-terminal His tag, expressed in E. coli, 50ug



  View other "CHUK" proteins (2)

USD 215.00


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    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human conserved helix-loop-helix ubiquitous kinase (CHUK), full length, with N-terminal His tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length CHUK
Tag N-His
Predicted MW 84.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, pH8.0,8M Urea.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001269
Locus ID 1147
Refseq Size 3539
Cytogenetics 10q24.31
Refseq ORF 2235
Synonyms IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16
Summary This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

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