NR1D1 (NM_021724) Human Recombinant Protein

CAT#: TP761441

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Purified recombinant protein of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), full length, with N-terminal HIS tag, expressed in E.coli, 50ug


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USD 205.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human nuclear receptor subfamily 1, group D, member 1 (NR1D1), full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Species Human
Expression Host E. coli
Tag N-His
Predicted MW 66.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
Reference Data
RefSeq NP_068370
Locus ID 9572
Refseq Size 2768
Cytogenetics 17q21.1
Refseq ORF 1842
Synonyms ear-1; EAR1; hRev; REVERBA; REVERBalpha; THRA1; THRAL
Summary This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Circadian rhythm - mammal

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