CACNB2 (NM_000724) Human Recombinant Protein

CAT#: TP761246

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Purified recombinant protein of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug



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USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length CACNB2
Tag N-His
Predicted MW 68 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000715
Locus ID 783
Refseq Size 3721
Cytogenetics 10p12.33-p12.31
Refseq ORF 1815
Synonyms CACNLB2; CAVB2; MYSB
Summary This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]
Protein Families Druggable Genome, Ion Channels: Other
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway

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