AKR1B15 (NM_001080538) Human Recombinant Protein

CAT#: TP761228

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Purified recombinant protein of Human aldo-keto reductase family 1, member B15 (AKR1B15), full length, with N-terminal HIS tag, expressed in E. coli, 50ug



USD 237.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human aldo-keto reductase family 1, member B15 (AKR1B15), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length AKR1B15
Tag N-His
Predicted MW 39.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001074007
Locus ID 441282
UniProt ID C9JRZ8
Cytogenetics 7q33
Refseq Size 951
Refseq ORF 1032
Synonyms AK1R1B7; AKR1B10L; AKR1R1B7
Summary Isoform 1: Catalyzes the NADPH-dependent reduction of a variety of carbonyl substrates, like aromatic aldehydes, alkenals, ketones and alpha-dicarbonyl compounds (PubMed:26222439, PubMed:21276782). In addition, catalyzes the reduction of androgens and estrogens with high positional selectivity (shows 17-beta-hydroxysteroid dehydrogenase activity) as well as 3-keto-acyl-CoAs (PubMed:25577493). Displays strong enzymatic activity toward all-trans-retinal and 9-cis-retinal (PubMed:26222439). May play a physiological role in retinoid metabolism (PubMed:26222439).[UniProtKB/Swiss-Prot Function]

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