PLA2G3 (NM_015715) Human Recombinant Protein

CAT#: TP761216

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Purified recombinant protein of Human phospholipase A2, group III (PLA2G3), full length, with N-terminal HIS tag, expressed in E. coli, 50ug



USD 215.00


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    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human phospholipase A2, group III (PLA2G3), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length PLA2G3
Tag N-His
Predicted MW 57 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_056530
Locus ID 50487
Refseq Size 2717
Cytogenetics 22q12.2
Refseq ORF 1527
Synonyms GIII-SPLA2; sPLA2-III; SPLA2III
Summary This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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