IL7 (NM_000880) Human Recombinant Protein

CAT#: TP761214

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Purified recombinant protein of Human interleukin 7 (IL7), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug



  View other "IL7" proteins (6)

USD 215.00


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    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interleukin 7 (IL7), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length IL7
Tag N-His
Predicted MW 17.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris, 8M Urea, pH8.0.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000871
Locus ID 3574
Refseq Size 2089
Cytogenetics 8q21.13
Refseq ORF 531
Synonyms IL-7
Summary The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. [provided by RefSeq, Dec 2010]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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Other Versions

Frequently bought together (1)
Anti-Human IL-7 Rabbit Polyclonal Antibody
    • 100 ug

USD 285.00

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