Cathepsin G(CTSG) (NM_001911) Human Recombinant Protein

CAT#: TP761143

Purified recombinant protein of Human cathepsin G (CTSG), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


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USD 205.00


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    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human cathepsin G (CTSG), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Species Human
Expression Host E.Coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length CTSG
Tag N-GST and C-His
Predicted MW 52.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Reference Data
RefSeq NP_001902
Locus ID 1511
Refseq Size 924
Cytogenetics 14q12
Refseq ORF 768
Synonyms CATG; CG
Summary The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]
Protein Families Protease, Druggable Genome
Protein Pathways Neuroactive ligand-receptor interaction, Lysosome, Renin-angiotensin system, Systemic lupus erythematosus

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