SPI1 (NM_003120) Human Recombinant Protein

CAT#: TP760228

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Recombinant protein of human spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


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USD 205.00


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    • 50 ug


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Product Data
Description Recombinant protein of human spleen focus forming virus (SFFV) proviral integration oncogene spi1 (SPI1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Species Human
Expression Host E. coli
Tag N-His
Predicted MW 30.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Reference Data
RefSeq NP_003111
Locus ID 6688
Refseq Size 1423
Cytogenetics 11p11.2
Refseq ORF 810
Synonyms OF; PU.1; SFPI1; SPI-1; SPI-A
Summary This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Transcription Factors
Protein Pathways Acute myeloid leukemia, Pathways in cancer

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