PCNA (NM_182649) Human Recombinant Protein

CAT#: TP750150

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Purified recombinant protein of Human proliferating cell nuclear antigen (PCNA), transcript variant 2, full length, tag free, expressed in E.Coli, 50 ug


Product Datasheet for 'TP750150'


  View other "PCNA" proteins (9)

USD 215.00


Availability*
2 Weeks

Size
    • 50 ug


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Specifications

Product Data
Description Purified recombinant protein of Human proliferating cell nuclear antigen (PCNA), transcript variant 2, full length, tag free, expressed in E.Coli, 50 ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding full-length of PCNA
Tag tag free
Predicted MW 28.8KDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20 mM Tris,pH7.5,2 mM EDTA,20% Glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_872590
Locus ID 5111
Refseq Size 1319
Cytogenetics 20p12.3
Refseq ORF 783
Synonyms ATLD2
Summary The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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