Il17a (NM_010552) Mouse Recombinant Protein

CAT#: TP723782

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Purified recombinant protein of Mouse interleukin 17A and 17F (Il17a / Il17f) heterodimer

Product Datasheet for 'TP723782'

  View other "Il17a" proteins (3)

USD 275.00

5 Days

    • 10 ug

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Product Data
Description Purified recombinant protein of Mouse interleukin 17A and 17F (Il17a / Il17f) heterodimer
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence Mouse IL-17A, the region of Ala26-Ala158, from gene Accession# NM_010552 and mouse IL-17F, the region of Arg29-Ala161, from gene Accession# NM_145856
Tag Tag Free
Predicted MW 30 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10 mM NaH2PO4, 0.15 M NaCl, pH7.2
Bioactivity The ED50 is 125 - 175 ng/ml, corresponding to a specific activity 0.57 - 0.8 x 10^4 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of IL-6.
Endotoxin Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_034682
Locus ID 16171
Refseq Size 1171
Cytogenetics 1 A4
Refseq ORF 477
Synonyms Ctla-8; Ctla8; IL-17; IL-17A; Il17
Summary This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]


Other Versions

Other products for "Il17a"
Frequently bought together (1)
Rat monoclonal Mouse IL-17A antibody
    • 100 ug

USD 530.00

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