GRO alpha (CXCL1) (NM_001511) Human Recombinant Protein

CAT#: TP723735

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Purified recombinant protein of Human chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1 / GRO-alpha)



  View other "CXCL1" proteins (2)

USD 170.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1 / GRO-alpha)
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence Human CXCL1, the region of Ala35 -Asn107, from gene Accession# NM_001511.2
Tag Tag Free
Predicted MW 7.8 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity Bioactivity was measured by its property to chemoattract human neutrophils in a dose dependent manner.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_001502
Locus ID 2919
Refseq Size 1184
Cytogenetics 4q13.3
Refseq ORF 321
Synonyms FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Summary This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway

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