IL1 alpha (IL1A) (NM_000575) Human Recombinant Protein

CAT#: TP723707

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Purified recombinant protein of Human interleukin 1, alpha (IL1A)



  View other "IL1A" proteins (4)

USD 275.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interleukin 1, alpha (IL1A)
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence Human IL-1alpha;, the region of Ser113-Ala271, from gene Accession# NM_000575
Tag Tag Free
Predicted MW 18 Da
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10mM NaH2PO4, 150mM NaCl, pH7.2
Bioactivity The ED50 is 5 - 15 pg/ml, corresponding to a specific activity of 0.6-2.0 x 10^7 units/mg, determined by the dose dependent stimulation of D10 cells proliferation.
Endotoxin Less than 0.01 ng per ug protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_000566
Locus ID 3552
Refseq Size 2943
Cytogenetics 2q14.1
Refseq ORF 813
Synonyms IL-1A; IL1; IL1-ALPHA; IL1F1
Summary The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus

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Other Versions

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IL1A mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
    • 100 ul

USD 379.00

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