WNT7A (NM_004625) Human Recombinant Protein

CAT#: TP723482

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Purified recombinant protein of Human wingless-type MMTV integration site family, member 7A (WNT7A).


 Product Datasheet for 'TP723482'

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USD 230.00

USD 399.00


Availability*
2 Weeks

Size
    • 15 ug


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Specifications

Product Data
Description Purified recombinant protein of Human wingless-type MMTV integration site family, member 7A (WNT7A).
Species Human
Expression Host HEK293
Tag Tag Free
Predicted MW 35.5 kDa
Concentration Resuspend the protein in the desired concentration in proper buffer
Purity >80% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity Determined by its ability to inhibit Wnt3a induced alkaline phosphatase production in MC3T3-E1 cells. The expected ED50 for this effect is 40-60 ng/ml.
Endotoxin Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Reference Data
RefSeq NP_004616
Locus ID 7476
Refseq Size 1732
Cytogenetics 3p25.1
Refseq ORF 1047
Synonyms AI849442; OTTMUSP00000024971; postaxial hemimelia; px; tw; wingless-related MMTV integration site 7A; Wnt-7a
Summary This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway

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