Vegfa (NM_001110336) Rat Recombinant Protein

CAT#: TP723470

Reviews ()
Write a review

Purified recombinant protein of Rat vascular endothelial growth factor A (Vegfa), transcript variant 5.

  View other "Vegfa" proteins (3)

USD 240.00

5 Days

    • 10 ug

Product images


Product Data
Description Purified recombinant protein of Rat vascular endothelial growth factor A (Vegfa), transcript variant 5.
Species Rat
Expression Host E. coli
Tag Tag Free
Predicted MW 38.5 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity Determined by the dose-dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0-8.0 ng/ml.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_001103806
Locus ID 83785
Refseq Size 2544
Cytogenetics 9q12
Refseq ORF 255
Synonyms Vegf; VEGF-A; VEGF111; VEGF164; VPF
Summary This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]


Other Versions

Other products for "Vegfa"
Frequently bought together (1)
Anti-Rat VEGF Antibody
    • 100 ug

USD 285.00

Customer Reviews 
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
Molbio tools