Thpo (NM_031133) Rat Recombinant Protein
Purified recombinant protein of Rat thrombopoietin (Thpo).
Specifications
Product Data | |
Description | Purified recombinant protein of Rat thrombopoietin (Thpo). |
Species | Rat |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence | SPVPPACDPRLLNKLLRDSYLLHSRLSQCPDVNPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPPQGRTTAHKDPSALFLSLQQLLRGKVRFLLLVEGPALCVRRTLPTTAVPSRTSQLLTLNKF |
Tag | Tag Free |
Predicted MW | 18.7 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2 |
Bioactivity | Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is less than or equal to 0.2 ng/ml, corresponding to a specific activity of > 5 x 10^6 units/mg. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_112395 |
Locus ID | 81811 |
Refseq Size | 1406 |
Cytogenetics | 11q23 |
Refseq ORF | 978 |
Summary | lineage-specific cytokine; important for proliferation and development of megakaryocytes and platelets; may be the major regulator of circulating platelets [RGD, Feb 2006] |
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