IL7 (NM_000880) Human Recombinant Protein

CAT#: TP723243

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Purified recombinant protein of Human interleukin 7 (IL7), transcript variant 1.


 Product Datasheet for 'TP723243'

  View other "IL7" proteins (8)

USD 230.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interleukin 7 (IL7), transcript variant 1.
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 17.4 kDa
Concentration Resuspend the protein in the desired concentration in proper buffer
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is less than or equal to 0.5 ng/ml, corresponding to a specific activity of > 2 x 10^6 units/mg.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq NP_000871
Locus ID 3574
Refseq Size 2089
Cytogenetics 8q21.13
Refseq ORF 531
Synonyms IL-7
Summary The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. [provided by RefSeq, Dec 2010]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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Other Versions

Frequently bought together (1)
Rabbit polyclonal IL-7 antibody Biotin Conjugated
    • 100 ug

USD 515.00

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