Ifng (NM_008337) Mouse Recombinant Protein
Purified recombinant protein of Mouse interferon gamma (Ifng).
|Description||Purified recombinant protein of Mouse interferon gamma (Ifng).|
|Expression Host||E. coli|
|Expression cDNA Clone or AA Sequence||MHGTVIESLESLNNYFNSSGIDVEEKSLFLDIWRNWQKDGDMKILQSQIISFYLRLFEVLKDNQAISNNISVIESHLITTFFSNSKAKKDAFMSIAKFEVNNPQVQRQAFNELIRVVHQLLPESSLRKRKRSRC|
|Predicted MW||15.6 kDa|
|Purity||>95% as determined by SDS-PAGE and Coomassie blue staining|
|Buffer||Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2|
|Bioactivity||Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is less than or equal to 0.2 ng/ml, corresponding to a specific activity of > 5 x 10^6 units/mg.|
|Endotoxin||Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)|
|Storage||Store at -80°C.|
|Stability||Stable for at least 6 months from date of receipt under proper storage and handling conditions.|
|Cytogenetics||10 66.75 cM|
|Summary||This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]|
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