Adipoq (NM_009605) Mouse Recombinant Protein

CAT#: TP723120

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Purified recombinant protein of Mouse adiponectin, C1Q and collagen domain containing (Adipoq).

  View other "Adipoq" proteins (3)

USD 240.00

5 Days

    • 25 ug

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Product Data
Description Purified recombinant protein of Mouse adiponectin, C1Q and collagen domain containing (Adipoq).
Species Mouse
Expression Host E. coli
Tag Tag Free
Predicted MW 16.6 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. ED50 for this effect is less than or equal to 15 ug/ml.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_033735
Locus ID 11450
UniProt ID Q60994
Cytogenetics 16 13.96 cM
Refseq Size 1233
Refseq ORF 741
Synonyms 30kDa; Acdc; Acrp30; Ad; Adid; adipo; apM1; APN; GBP28
Summary Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.[UniProtKB/Swiss-Prot Function]


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