IL18R Beta (IL18RAP) (NM_003853) Human Recombinant Protein

CAT#: TP721078

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Purified recombinant protein of Human interleukin 18 receptor accessory protein (IL18RAP)

Product Datasheet for 'TP721078'

  View other "IL18RAP" proteins (3)

USD 300.00

2 Weeks

    • 10 ug

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Product Data
Description Purified recombinant protein of Human interleukin 18 receptor accessory protein (IL18RAP)
Species Human
Expression Host HEK293
Tag C-Fc/His
Predicted MW 66.4 kDa
Concentration Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM PB,150mM NaCl,pH7.2
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_003844
Locus ID 8807
Refseq Size 2672
Cytogenetics 2q12.1
Refseq ORF 1797
Synonyms ACPL; CD218b; CDw218b; IL-1R-7; IL-1R7; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL18RB
Summary The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction


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