Caspase 10 (CASP10) (NM_032977) Human Recombinant Protein

CAT#: TP720939

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Purified recombinant protein of Human caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant 1

  View other "CASP10" proteins (1)

USD 300.00

2 Weeks

    • 10 ug

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Product Data
Description Purified recombinant protein of Human caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant 1
Species Human
Expression Host E. coli
Tag C-His
Predicted MW 30.1 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 µM filtered solution of 25mM HEPES, 10mM DTT, pH 7.5
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at -80°C.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_116759
Locus ID 843
UniProt ID Q92851, A0A0S2Z3Z5
Cytogenetics 2q33.1
Refseq Size 5906
Refseq ORF 1566
Synonyms ALPS2; FLICE2; MCH4
Summary This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Protein Families Druggable Genome, Protease
Protein Pathways Apoptosis, RIG-I-like receptor signaling pathway


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