Carbonic Anhydrase III (CA3) (NM_005181) Human Recombinant Protein

CAT#: TP720887

Purified recombinant protein of Human carbonic anhydrase III, muscle specific (CA3)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Ala2-Lys260
• Tag: C-His
• Predicted MW: 30.6 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_005172
• Locus ID: 761
• UniProt ID: P07451, V9HWA3
• Cytogenetics: 8q21.2
• Refseq Size: 1753
• Refseq ORF: 780
• Synonyms: CAIII; Car3
• Summary: Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]
• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism