Calcineurin B (PPP3R1) (NM_000945) Human Recombinant Protein

CAT#: TP720542

Recombinant protein of human protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform (PPP3R1)

Product images

Specifications

Product Data

• Description: Recombinant protein of human protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform (PPP3R1)
• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence: A DNA sequence from TrueORF clone, RC206585, encoding the full length polypeptide (Met1-Val170) of human PPP3R1
• Tag: N-His
• Predicted MW: 21.5 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 100mM NaCl, 2mM DTT, pH 8.0.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_000936
• Locus ID: 5534
• Refseq Size: 3111
• Cytogenetics: 2p14
• Refseq ORF: 510
• Synonyms: CALNB1; CNB; CNB1
• Summary: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway