Integrin alpha 5 (ITGA5) (NM_002205) Human Recombinant Protein
Recombinant protein of human integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5)
Specifications
Product Data | |
Description | Recombinant protein of human integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | A DNA sequence from TrueORF clone, RC201151, encoding the secreted form (Phe42-Tyr995) of human ITGA5 |
Tag | N-GST |
Predicted MW | 105.1 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002196 |
Locus ID | 3678 |
Refseq Size | 4267 |
Cytogenetics | 12q13.13 |
Refseq ORF | 3147 |
Synonyms | CD49e; FNRA; VLA-5; VLA5A |
Summary | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
Documents
FAQs |
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Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400803 | ITGA5 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 110.00 |
|
LY400803 | Transient overexpression lysate of integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5) |
USD 360.00 |
|
PH301151 | ITGA5 MS Standard C13 and N15-labeled recombinant protein (NP_002196) |
USD 2,260.00 |
|
TP301151 | Recombinant protein of human integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5) |
USD 748.00 |
USD 345.00