Integrin alpha 5 (ITGA5) (NM_002205) Human Recombinant Protein

CAT#: TP720399

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Recombinant protein of human integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5)


Product Datasheet for 'TP720399'


  View other "ITGA5" proteins (4)

USD 300.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC201151, encoding the secreted form (Phe42-Tyr995) of human ITGA5
Tag N-GST
Predicted MW 105.1 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_002196
Locus ID 3678
Refseq Size 4267
Cytogenetics 12q13.13
Refseq ORF 3147
Synonyms CD49e; FNRA; VLA-5; VLA5A
Summary The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

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Other Versions

Other products for "ITGA5"
Frequently bought together (1)
Rabbit polyclonal ITGA5 (heavy chain, Cleaved-Phe42) antibody
    • 100 ul

USD 345.00

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