Junctional Adhesion Molecule 1 (F11R) (NM_016946) Human Recombinant Protein
CAT#: TP720393
Recombinant protein of human F11 receptor (F11R)
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ser28-Val238
|
Tag | C-His |
Predicted MW | 23.9 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_058642 |
Locus ID | 50848 |
UniProt ID | Q9Y624, Q6FIB4 |
Cytogenetics | 1q23.3 |
Synonyms | CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1 |
Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403392 | F11R HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC413796 | F11R HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC429529 | F11R HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY403392 | Transient overexpression lysate of F11 receptor (F11R), transcript variant 5 |
USD 436.00 |
|
LY413796 | Transient overexpression lysate of F11 receptor (F11R) |
USD 436.00 |
|
PH300004 | F11R MS Standard C13 and N15-labeled recombinant protein (NP_653087) |
USD 3,255.00 |
|
PH321478 | F11R MS Standard C13 and N15-labeled recombinant protein (NP_058642) |
USD 3,255.00 |
|
TP300004 | Recombinant protein of human F11 receptor (F11R), transcript variant 5, 20 µg |
USD 867.00 |
|
TP321478 | Recombinant protein of human F11 receptor (F11R), 20 µg |
USD 867.00 |
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