HMG1 (HMGB1) (NM_002128) Human Recombinant Protein

CAT#: TP720309

Recombinant protein of human high-mobility group box 1 (HMGB1)


 Product Datasheet for 'TP720309'

 Cited in 1 publication.

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USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Description Recombinant protein of human high-mobility group box 1 (HMGB1)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC205918, encoding the polypeptide (Gly2-Glu215) of human HMBG1
Tag C-His
Predicted MW 25.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20mM Phosphate buffer, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH 7.4.
Bioactivity ELISA capture for autoantibodies (PMID: 28862243)
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_002119
Locus ID 3146
Refseq Size 3428
Cytogenetics 13q12.3
Refseq ORF 648
Synonyms HMG-1; HMG1; HMG3; SBP-1
Summary This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Base excision repair

Citations (1)

Documents

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